ABSTRACT
384 cholecystectomy specimens were examined during a period of one year from Oct 2005 to Oct 2006, in the department of Pathology, ASCOMS, Sidhra. Jammu, for studying the histological patterns of chronic cholecystitis, the frequency of associated mucosal changes, the age related incidence and the relationship of carcinoma with various mucosal changes. Majority of patients presented in the fourth decade of life. The youngest patient was 16 years and the oldest 78 years of age. Acute and chronic inflammatory lesions were associated with ulceration in 13.02%, mucosal hyperplasia in 25.26% and antral metaplasia in 53.40%. Intestinal metaplasia constituted 9.11%, cholesterolosis was seen in 12.25%, dysplasia in 3.64% and neoplasia in 0.78% of cases. All the cases of carcinoma were associated with gallstones. Histological continuity between epithelial changes was seen in 35 cases. 8 cases had continuity of antral metaplasia, intestinal metaplasia and dysplasia. 2 cases showed continuity of intestinal metaplasia with dysplasia and carcinoma and 1 case showed continuity of dysplasia with carcinoma.It is inferred that antral metaplasia, intestinal metaplasia, dysplasia and carcinoma have an inter-relationship. There is a significant higher incidence of carcinoma gallbladder in patients who harbor gallstones for longer period. Histopathological examination is thus important in every case of cholecystectomy for identifying metaplasia, dysplasia and carcinoma.
ABSTRACT
The present randomized study was undertaken to study cytological features of non-neoplastic and neoplastic lesions of enlarged lymph nodes by FNAC in 656 patients presenting with lymphadenopathy in the Postgraduate Department of Pathology of Government Medical College, Jammu over a period of three year. Tuberculous lymphadenitis, reactive hyperplasia, metastatic carcinoma, pyogenic lymphadenitis and lymphomas were seen in 52.3%, 37.2%, 3.8%, 1% and 2% respectively. However, a solitary case of Langerhans histiocytosis in a three year old child was reported over three years. Reactive hyperplasia was seen most often (74.5%) in first two decades of life, 58.9% tuberculous lymphadenitis in the second and third decades and 88% of metastatic carcinoma over 40 years of age. Cases of lymphoma were distributed in all age groups. Males showed preponderance of reactive hyperplasia, lymphoma and metastatic carcinoma, while tuberculous lymphadenitis showed a slight female preponderance. Cervical lymph nodes were involved most often in all types of lymphadenopathy.
ABSTRACT
The chief mineral source of Jammu province is bauxite, an aluminium ore, so a possibility of water being heavily polluted with aluminium is prevalent. Hence, in an effort to relate this regional geographical aspect with aluminium bone disease (ABD) in chronic renal failure (CRF), 50 cases of CRF were prospectively evaluated. Patients were subjected to a thorough history and clinical examination. Biochemical parameters along with raiological skeletal survey and iliac crest bone biopsies were undertaken. Sixty-eight per cent of CRF patients were also consuming aluminium containing phosphate binders (ACPB) at that time. The study revealed an occurrence of ABD in 10% of CRF patients. It was found predominantly superimposed upon osteomalacia (8%) and mixed osteodystrophy (2%). Superimposed ABD on osteomalacia was found more frequently in pre-dialysis (10.8%) than after haemodialysis group (7.69%). Moreover, the incidence of ABD superimposed on osteomalacia and mixed osteodystrophy was higher in the ACPB group (14.7%) than the post-haemodialysis group (7.69%). Correlating, the pre-dialysis, post-haemodialysis and ACPB ingestion status of CRF patients on one hand and histologically proven ABD on the other, it was deduced that the majority of cases of CRF having ABD was seen in ACPB ingestion group (14.7%) followed by pre-dialysis (10.8%) and post-haemodialysis (7.69%) groups. Thus it was concluded that in the present work, ACPB ingestion was the major source of aluminium deposition in bones of patients with CRF rather than the water used in dialysis or possible pollution of drinking water with aluminium in our province.
ABSTRACT
Pilomatrixoma or calcifying epithelioma of Malherbe is one of benign adenexal tumors of the skin. !t occurs in all the age groups with common locations in the head and neck region. Fine needle aspiration cytology has a challenge in the diagnosis of these tumors.We report a similar case of calcifying epithelioma.
ABSTRACT
Malignant transformation in a benign cystic teratoma occurs in 1-3% of cases. A rare case of squamous cell carcinoma arising in a benign cystic teratoma of ovary in a 37 year old female is reported. The patient presented with increasing abdominal girth and pain abdomen and was clinically diagnosed having a large ovarian cyst.
ABSTRACT
A mucus producing adenomatous tumor, adenocarcinoma of the renal pelvis has been one of the rarest tumors ofthe genito-urinary tract. Presented here is a case report ofa patient who was admitted with pain and lump left loin and was operated upon. The gross morphology and histological features of the specimen were consistent with mucin-secreting adeno-carcinoma ofthe kidney.
ABSTRACT
2681 histologically confirmed cases of cancer (1402 males and 1279 females) were seen during the ten year period 1978 to 1987 in Pathology Department, Government Medical College, Jammu. The relative frequencies of cancer at various primary sites have been determined with respect to age, sex and religion. The majority of cancers were seen between 31-60 years (67.7%) with a peak in 41-50 years age group. Out of the total cancer patients 2,437 were Hindus (90.8%) and 244 were Muslims (9.2%). The most common cancer sites among males were lung, skin, larynx, prostate and lymphnodes. Cancer cervix was the most common tumor in females, followed by cancer breast, gall bladder and uterus. Among Muslims, cancer cervix and penis were infrequent. Cancer lung and larynx were also relatively less frequent in Muslims.